A medical procedure localization aid produces reference marks on both the patient and the medical imaging scan. The aid is defined by a substrate sheet having indicia on one side that is opaque to medical imaging radiation and indicia on a second side that is transferable to a patient. The indicia on the first side is displayed on the scan image and the indicia on the second side is imprinted on the patient. By visualizing the location of a target on the scan image relative to the indicia on the scan image and comparing that with indicia on the patient, a medical professional may reliably locate where a medical procedure should be performed.