The mouthpiece carrier assembly (12) is adapted and configured to receive the upper and lower teeth of the user. The mouthpiece carrier assembly is driven such that the bristles mounted on the teeth-facing surfaces of the mouthpiece assembly contact said surfaces and provide a cleaning effect therefor. A plurality of bristle sections (30, 32, 34, 41, 44) are secured to the teeth-facing portions of the mouthpiece assembly, wherein the bristle sections each have bristles which have a particular configuration and are otherwise adapted to provide effective cleaning for an associated dental region.