The invention discloses a kind of composition, the composition may include 4 O glucosiduronic acids epicatechin (4GEC) of flavanols metabolin.In some embodiments, the composition can be used for blood vessel dilatation and/or increase the method for the blood flow delivering for flowing to the tissue in body, such as by the way that the composition to be administered to the individual suffered from or in hypertension or risk of cardiovascular diseases.In some embodiments, the composition is used for weight maintenance or weight loss.The composition is oral preferably as food product, wherein 4 the O glucosiduronic acids epicatechin exists with the concentration of at least 0.01mg/g of the food product.
