KOIKE Masamichi,SPITALNY George L.,WHEELER Alistair,WHITE Barbara
申请号:
SI200831561
公开号:
SI2068927T1
申请日:
2008.05.14
申请国别(地区):
SI
年份:
2016
代理人:
摘要:
The present invention relates to an antibody that binds IL-5R for use in reducing the numbers of basophils in a human subject. In a specific embodiment, the antibody is administered parenterally. In another specific embodiment, the post-administration reduction in absolute basophil count is of at least about 5, at least about 10, at least about 15, at least about 20, at least about 25, at least about 30, at least about 35, at least about 40, at least about 45, at least about 50, at least about 55, at least about 60, at least about 65, or at least about 70 basophils/mm 3 .