COSFORD NICHOLAS D P,HAUNG DEHUA,ROPPE JEFFREY R,SMITH NICHOLAS D,TEHRANI LIDA R
申请号：
IN4298/DELNP/2005
公开号：
IN252150B
申请日:
2005.09.22
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
Pyrrole compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof (where A, B, R11, R12, R13, w, X, Y and Z are as defined herein), which are substituted directly, or by a bridge, with i) a heteroaryi moiety containing N adjacent to the point of connection of the heteroaryi and ii) another heteroaryi or aryl ring, with at least one of the rings being further substituted with another ring, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, panic, and bipolar disorder, as well as in the treatment of pain, Parkinsons disease, cognitive dysfunction, epilepsy, circadian rhythm disorders, drug addiction, drug abuse, drug withdrawal, obesity and other diseases.
