The present invention aims to provide a means for effectively and conveniently treating diseases wherein corneal endothelial cells poor in proliferative capacity in vivo are damaged. The present invention provides a therapeutic agent for corneal endothelial dysfunction containing (R) ( + ) N (1H pyrrolo [2,3 - b] pyridin 4 - yl) - 4 - (1 aminoethyl) benzamide or a pharmacologically acceptable salt thereof (compound (Ia) ) as active ingredient an agent for promoting adhesion of corneal endothelial cells containing compound (Ia), a culture medium for corneal endothelial cells containing the agent for promoting adhesion an implant for corneal endothelial keratoplasty, containing corneal endothelial cells scaffold and compound (Ia), and a production method of a corneal endothelial preparation, including a step of cultivating corneal endothelial cells using the culture medium.
