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Synthetic peptides that induce expression of type 2 TNF receptor and use thereof
专利权人:
東亞合成株式会社
发明人:
小林 菜穂子,吉田 徹彦,丹羽 幹夫
申请号:
JP2013513074
公开号:
JP5967448B2
申请日:
2012.04.17
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
This invention provides a TNFR2 expression-inducing composition comprising as an active ingredient a peptide having TNFR2 expression-inducing activity, and a method for producing cells that express TNFR2 selectively by use of the composition. The cell production method provided by this invention comprises: culturing at least one species of cells capable of expressing TNF receptor 2, and supplying the cells with a synthetic peptide consisting of a nuclear localization signal sequence (NLS) or a nucleolar localization signal sequence (NoLS) to enhance TNFR2 expression in the cells.
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