THE GENERAL HOSPITAL CORPORATION;Andrew S. CHI;MACROGENICS INC.
发明人:
Andrew S. CHI
申请号：
IL24726716
公开号：
IL247267D0
申请日:
2016.08.14
申请国别(地区):
IL
年份:
2016
代理人:
摘要：
The invention concerns therapeutic compositions for the treatment of vascularizing cancers, especially, glioblastoma. In particular, the invention is directed to compositions that comprise a molecule having a binding ability that is specific for B7-H3 and a molecule having a binding ability that is specific for a cell-surface factor (or its receptor) that is involved in promoting tumor angiogenesis (especially VEGF or its receptor, VEGFR). The invention is additionally directed to the use of such compositions in the treatment of such cancers, and in particular, in the treatment of glioblastoma.
