ANALOGUES DE QUINAZOLINE COMME INHIBITEURS DU RECEPTEUR DE LA TYROSINE KINASE

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专利权人:

ARRAY BIOPHARMA; INC.

发明人:

申请号：

EP04780990.0

公开号：

EP1660090B1

申请日:

2004.08.10

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

This invention provides quinazoline analogs of Formula I: where A is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

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