用於治療認知及睡眠障礙，肥胖及其他中樞神經系統異常之做為組織胺３受體抑制劑之吲哚衍生物农业专利-农业学术服务平台

发明人:: BENNANI, YOUSSEF L.,约瑟夫Ｌ　班那尼,約瑟夫Ｌ　班那尼,CAMPBELL, MICHAEL G.,麦可Ｇ　坎贝尔,麥可Ｇ　坎貝爾,DASTRUP, DAVID,大卫　达斯塔卜,大衛　達斯塔卜,PORTER HUCK, EMILIE,艾米力　波特　浩克,约瑟夫L 班那尼,約瑟夫L 班那尼,麦可G 坎贝尔,麥可G 坎貝爾,大卫达斯塔卜,大衛達斯塔卜,艾米力波特浩克

摘要：: This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.本發明係關於具有藥理學活性之化合物、含有此等化合物之組合物，及一種採用該等化合物及組合物進行治療之方法。更具體而言，本發明係關於特定吲哚衍生物及其鹽類及溶劑化物。此等化合物具有H3組織胺受體拮抗劑活性。本發明亦係關於含有此等化合物之醫藥組合物及一種治療可受益於組織胺H3受體阻斷之病症的方法。