Stephane Birkle,Denis Cochonneau,Mylene Dorvillius,Jean-Marc Le Doussal,Mickael Terme
申请号:
US14787707
公开号:
US10000575B2
申请日:
2014.04.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An antibody recognizing the O-acetylated-GD2 ganglioside for the treatment of Cancer Stem Cells (CSC) cancer, a pharmaceutical composition including the antibody for treating a CSC cancer and a method for treating a CSC cancer in a patient in need thereof, the method including administering the antibody to the patient. A method for diagnosing a CSC, the use of the O-acetylated-GD2 ganglioside as a biomarker of CSC cancer, and a method for predicting the response of a subject affected with CSC cancer to a treatment with the antibody or the composition are also described.