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PROCEDE POUR LA RECONSTITUTION D'UNE FORME SOLIDE D'UNE COMPOSITION PHARMACEUTIQUE
专利权人:
UCB BIOPHARMA SPRL;EVEON
发明人:
PAYET-BURIN, XAVIER
申请号:
CA2936721
公开号:
CA2936721A1
申请日:
2015.01.20
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention relates to a process for reconstitution of a solid form of a pharmaceutical composition, comprising the following successive steps: (i) providing the solid form of the pharmaceutical composition in a sealed container, the pressure within the container being an initial pressure (pi,) comprised between 0.5 Pa and 1.2x105 Pa; (ii) at a first time point (t0) introducing the solvent into said sealed container and maintaining the resulting pressure (pr) within the container during a controlled time ?t1; and (iii) at a second time point (t2) increasing the pressure within the container to a controlled pressure (p2) higher than said resulting pressure (pr) until complete reconstitution.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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