PHARMACEUTICAL COMPOSITION COMPRISING (1R,4R)-6-FLUORO-N,N-DIMETHYL-4-PHENYL-4,9-DIHYDRO-3H-SPIRO[CYCLOHEXANE-1,1-PYRANO [3,4,B]INDOL]-4-AMINE AND A NSAR
The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from (1r,4r)-6&prime-fluoro-N,N-dimethyl-4-phenyl-4&prime,9&prime-dihydro-3&primeH-spiro[cyclohexane-1,1&prime-pyrano[3,4,b]indol]-4-amine and the physiologically acceptable salts thereof, and a second pharmacologically active ingredient which is a non-steroidal anti-rheumatic drug selected from the group consisting of indometacin, diclofenac, sulindac, tolmetin, zomepirac, aclofenac, bumadizone, etodolac, lonazolac, fentiazac, acemetacin, difenpiramide, oxametacin, proglumetacin, ketorolac, aceclofenac, bufexamac, mefenamic acid, tolfenamic acid, flufenamic acid, meclofenamic acid, and the physiologically acceptable salts thereof.
