Fibronectin: growth factor chimeras

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专利权人:

QUEENSLAND UNIVERSITY OF TECHNOLOGY

发明人:

UPTON ZEE,VAN LONKHUYZEN DEREK

申请号：

NZ60045410

公开号：

NZ600454A

申请日:

2010.11.30

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Discloses a protein complex in the form of a synthetic chimeric protein comprising an amino acid sequence of (I) an insulin-like growth factor (IGF, IGF-I or IGF-II) or at least a domain of said insulin-like growth factor which is capable of binding a cognate insulin-like growth factor receptor and (II) one or more type-III domains of fibronectin (FN3) comprising at least an integrin-binding domain of FN3； wherein the complex is suitable for stimulating cell migration and/or proliferation

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