The invention provides a method for supporting operational activities in daily living by providing a combination of (a) long-chain polyunsaturated fatty acids, particularly DHA and/or EPA, and (b) nucleosides or nucleotides, particularly uridine or its equivalent. The operational activities comprise eating ； walking ； toileting ； bathing ； grooming ； dressing； use of communication equipment ； making conversations ； keeping appointments ； use of household appliances ； cleaning dishes ； preparation of meal or drink ； writing ； reading ； independent housekeeping ； transportation and shopping.
