Kevin D'Amour;Emmanuel Edward Baetge;Laura Martinson;Evert Kroon
发明人:
Laura Martinson,Evert Kroon,Kevin D'Amour,Emmanuel Edward Baetge,Kevin DAmour
申请号：
US13205511
公开号：
US09585917B2
申请日:
2011.08.08
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.
