Method for delivering agents into cells using bacterial toxins

• 收藏
• 分享

专利权人:

President and Fellows of Harvard College

发明人:

Collier, Robert J.,Pentelute, Brad L.

申请号：

AU2012205772

公开号：

AU2012205772A1

申请日:

2012.01.10

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The invention provides compositions and methods for delivering a bioactive moiety comprising at least one non-natural component into a cell cytosol of an eukaryotic cell. The bioactive moiety is linked to an A component of a bacterial toxin, a functional wild-type or modified fragment thereof, or an A component surrogate or mimetic. For delivery, the cell is contacted with the linked bioactive moiety and a corresponding B component of the bacterial toxin or a functional fragment thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/