According to embodiments, a membrane with flat or curved surface is provided for protection of intraocular tissues. The membrane can be used to cover the cornea for protecting cornea endothelial cells cover the anterior and posterior surface of iris, or cover the surface of posterior capsule for separating the intraocular tissues. The membrane has a layered structure, which is composed of a collagen and a hydrophilic biopolymer or an organic polymer materials. In particular, the membrane has high transparency and high water retention in the wet state.本發明提供一種具有保護眼內組織之平面或弧形曲面的薄膜。該薄膜可用於覆蓋眼角膜內皮細胞層,或鋪蓋於虹膜前後表面,或水晶體後囊袋前,以達到保護角膜內皮細胞,或區隔眼內組織之目的。該薄膜為一膠原蛋白及一親水性生物高分子或有機高分子材料所構成的層狀結構,且在吸水濕潤的狀態下,具有高透明度及高保水度之特性。