A synergistic insecticidal composition comprises component (A), at least one neonicotinoid insecticide, and component (B), at least one avermectin insecticide. There is also provided a method to prevent, control and/or treat insect infestations in plants, plant parts and/or surrounding by applying a combination of component (A), at least one neonicotinoid insecticide, and component (B), at least one avermectin insecticide. The exemplified compositions are imadacloprid in combination with abamectin or emamectin benzoate. The plants treated in the examples include tomatoes, oranges, pummelo, pistachio, cotton, coffee, melon, potatoes, red pepper, soybean and roses. The insects targeted include Spider mites, Leafminers, Asian citrus psyllid, red mites, Stink bugs, thrips, aphids, whiteflies, Pistachio psyllae and moths.