PROBLEM TO BE SOLVED: To provide a method for producing a homogeneous gel-like composition which contains active ingredients in water-soluble substance, such as, a water-soluble medical agent at a high concentration, in which the water-soluble substance and thickening polysaccharide are dispersed homogeneously and dissolved, and which will not cause undissolved lumps of flour and aggregated substance.SOLUTION: The method for producing a gel-like composition containing 5 mass% of the water-soluble substance includes a process (A) of preliminarily mixing thickening polysaccharide and low-molecular saccharide with each other so as to have 3 pts.mass or higher for the low-molecular saccharide, based on 1 mass% of the thickening polysaccharide to obtain a thickening polysaccharide solution and a process (B) of adding the water-soluble substance to the thickening polysaccharide solution so that the final concentration of the solution is 5 mass% or higher, to obtain a solution that contains the thickening polysaccharide and the water-soluble substance.COPYRIGHT: (C)2009,JPO&INPIT【課題】水溶性物質、例えば、水溶性の薬剤などの有効成分を高濃度で含み、かつ水溶性物質および増粘多糖類が均一に分散・溶解し、ダマおよび塊状物質が生じない均質なゲル状組成物の製造方法を提供すること。【解決手段】本発明は、水溶性物質を5質量%以上含むゲル状組成物の製造方法を提供し、該方法は、(A)増粘多糖類と、低分子糖類とを混合して増粘多糖類溶液を得る工程であって、該増粘多糖類1質量部に対して、該低分子糖類が3質量部以上となるように予め混合する工程、および(B)該増粘多糖類溶液に、該水溶性物質を最終濃度が5質量%以上となるように添加して、増粘多糖類と水溶性物質とを含む溶液を得る工程を包含する。【選択図】なし
