PRICE, STEPHEN,HEALD, ROBERT,LEE, WENDY,ZAK, MARK E.,HEWITT, JOANNE FRANCES MARY
申请号:
CA2706571
公开号:
CA2706571C
申请日:
2008.12.18
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to imidazopyridines of formula I with anti-cancer and/oranti-inflammatoryactivity and more specifically to imidazopyridines which inhibit MEK kinaseactivity. Theinvention provides compositions and methods useful for inhibiting abnormalcell growth ortreating a hyperproliferative disorder, or treating an inflammatory disease ina mammal. Theinvention also relates to methods of using the compounds for in vitro, insitu, and in vivodiagnosis or treatment of mammalian cells, or associated pathologicalconditions.(see formula I)