DISCLOSED ARE ORAL CARE COMPOSITIONS AND THE USE OF SUCH ORAL CARE COMPOSITIONS FOR TREATING CONDITIONS CAUSED BY BIOFILM FORMATION. ALSO DISCLOSED ARE METHODS FOR INHIBITING BIOFLIM FORMATION AND/OR DEGRADING BIOFLIM. THE ORAL CARE COMPOSITION INCLUDES A SESQUITERPENOID AND AN ANTIMICROBIAL AGENT, IN WHICH THE SESQUITERPENOID AND THE ANTIMICROBIAL AGENT ARE PRESENT IN AN AMOUNT EFFECTIVE TO INHIBIT AND/OR DEGRADE A BIOFLIM IN THE ORAL CAVITY.