A method for reconstructing list mode data comprises: reconstructing all list mode data of a list mode data set (30, 160) to generate a first reconstructed image (32, 62) selecting a sub-set of the list mode data set and reconstructing the sub-set of the list mode data set to generate an enhanced reconstructed image (84, 86). An image generation system comprises: a reconstruction module (24) configured to perform a standard reconstruction of a list mode data set to generate a standard reconstructed image (32, 62) and a re reconstruction module (24, 70, 80, 82, 150, 152, 154) configured to perform a reconstruction other than the standard reconstruction of at least a portion of the list mode data set to generate an enhanced reconstructed image (84, 86).
