COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION;GRAINS RESEARCH AND DEVELOPMENT CORPORATION
发明人:
Petrie James Robertson,Mackenzie Anne Maree,Liu Qing,Shrestha Pushkar,Nichols Peter David,Blackburn Susan Irene Ellis,Mansour Maged Peter,Robert Stanley Suresh,Frampton Dion Matthew Frederick,Zhou Xue-Rong,Singh Surinder Pal,Wood Craig Christopher
申请号：
US201715661673
公开号：
US9976107(B2)
申请日:
2017.07.27
申请国别(地区):
美国
年份:
2018
代理人:
White John P.`Gershik Gary J.`Cooper & Dunham LLP
摘要：
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
