A compound of Formula I: ** Formula ** wherein: is phenyl, pyridyl, pyrimidyl, pyrazinyl or pyridazyl； R1 is Cl, -CN, H, F, OC (1-4) alkyl, OCHF2, ** Formula ** OCF3, C (1-4) alkyl, Br, I, or cyclopropyl； wherein said C (1-4) alkyl is optionally substituted with up to six fluorine atoms； R2 is F, Cl, -CN, H, O-C (1-4) alkyl, OCHF2, OCF3, cyclopropyl or C (1-4) alkyl； wherein said C (1-4) alkyl is optionally substituted with up to five fluorine atoms, and said cyclopropyl is optionally substituted with OH, CH3, CF3, and up to five fluorine atoms； or R1 and R2 can be taken together with their attached ring A to form a fused ring system selected from the group consisting of naphthalenyl, tetrahydronaphthalenyl, isoquinolinyl, quinolinyl, 2,3-dihydro-1H-indenyl, chromanyl, isochromanyl, and naphthyridinyl； wherein said naphthalenyl, tetrahydronaphthalenyl, isoquinolinyl, quinolinyl, 2,3-dihydro-1H-indenyl, chromanyl, isochromanyl, and naphthyridinyl may be optionally substituted with up to three substituents independently selected from the group consisting of F, OC (1-3) alkyl or C (1-3) alkyl wherein said OC (1-3) alkyl and C (1-3) alkyl is optionally substituted with up to five fluorine atoms (including CHF2, CH2F, CF3 and CH3； provided that R2 is not H if R1 is H； R3 is thiadiazolyl, oxadiazolyl, isoxadiazolyl, oxazolyl, isoxazolyl, triazolyl, tetrazolyl, 1,2,4-oxadiazol-5 (4H) -on-3-yl, pyridyl, thiazolyl, pyrimidyl, pyridazyl, pyrazyl, imidazolyl, pyrrolyl, furanyl, or phenyl； wherein said thiadiazolyl, oxadiazolyl, isoxadiazolyl, oxazolyl, isoxazolyl, triazolyl, pyridyl, thiazolyl, pyrimidyl, pyridazyl, pyrazyl, imidazolyl, pyrrolyl, R4, optionally substituted with phenyl and additionally optionally substituted with u n substituent selected from the group consisting of F, CH3, CF3, and cyclopropyl； R4 is H, C (1-6) alkylSO2 C (1-6) alkyl, C (O) NH2, C (1-6) alkyl, -CN, C (3-6) cycloalkyl, NH2, NH (C ( 1-6) alkyl), N (C (1-6) alkyl) 2, NHCO (C (1-6) alkyl), N (C (1
