RIBONUCLEOTIDE REDUCTASE INHIBITORS AND METHODS OF USE

• 收藏
• 分享

专利权人:

CITY OF HOPE

发明人:

HORNE, DAVID,LINCOLN, CHRISTOPHER

申请号：

EP13743552

公开号：

EP2809662A4

申请日:

2013.02.01

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme, as well as methods of synthesizing these novel compounds. The compounds may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/