Petra Marcella Francoise Blom,Jan Marie Cyriel Jozef Hoflack
申请号:
US14744154
公开号:
US09370519B2
申请日:
2015.06.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of FLT3 (FMS-Related Tyrosine kinase 3). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine, in particular for the treatment of cell proliferative disorders, such as cancer.