T S SAMPATH KUMAR,T S SAMPATH KUMAR,MADHUMATHI K,MADHUMATHI K
申请号:
IN1039/CHE/2014
公开号:
IN2014CH01039A
申请日:
2014.02.28
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
A novel bioceramic nanocarrier formulation based bone filler with multi-drug delivery mechanism. Calcium phosphate ceramic nanoparticles (e.g., HA, CDHA, and /3-TCP nanoparticles) are synthesized at optimal conditions in order thereby use the nanoparticles as bone fillers for infected parts of human body in wide range of surgical applications. The synthesized calcium phosphate ceramic nanoparticles are loaded with multiple drug compositions which enables the bone filler nanoparticles to act as local drug delivery systems. The nanoparticles are capable of simultaneously releasing multiple drug compositions thereby functioning as enhanced bone fillers with multi-drug delivery features.