An oxygen generating wound dressing is provided. The oxygen generating wound dressing comprises a housing and a wound contacting layer. The interior of the housing comprises a barrier board for separating a reactant containing receptacle and a wound contacting layer containing receptacle. The reactant containing receptacle of the housing further comprises a first reactant containing receptacle, a second reactant containing receptacle, a check valve disposed between the first reactant containing receptacle and the second reactant containing receptacle, a flow regulating means disposed on the second reactant containing receptacle and a gas deliver tube for connecting the first reactant containing receptacle and the wound contacting layer containing receptacle. The entrance speed of the second reactant into the first reactant containing receptacle can be controlled by the flow regulating means. The oxygen partial pressure can be maintained preferably and the wound healing can be improved by using the oxygen generating wound dressing of the present invention.一種產氧傷口敷料,其包含一殼體以及一傷口接觸層。殼體內具有一阻隔部以將殼體分隔為一反應物容受空間以及一傷口接觸層容受空間。反應物容受空間包含一第一反應物容受空間、一第二反應物容受空間、設於第一反應物容受空間以及第二反應物容受空間之間的逆止閥、設於第二反應物容受空間上的流量調節裝置以及可氣體連通第一反應物容受空間以及傷口接觸層容受空間的氣體輸送導管。流量調節裝置係用以控制第二反應物經由逆止閥進入第一反應物容受空間之速度。利用本創作之產氧傷口敷料可較佳地維持傷口周圍的氧氣分壓,並可促進傷口癒合。