PROCEDES DE PRODUCTION DE CELLULES IMMUNITAIRES REGULATRICES ET LEURS UTILISATIONS

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专利权人:

THE UNIVERSITY OF TEXAS SYSTEM;BOARD OF REGENTS

发明人:

REZVANI, KATY,SHPALL, ELIZABETH,BASAR, RAFET

申请号：

CA3068286

公开号：

CA3068286A1

申请日:

2018.06.22

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Provided herein are methods for expanding populations of regulatory B cells comprising treating a population of B cells with IL-4 and CD40 ligand. Further provided herein are methods of expanding populations of regulatory T cells comprising expanding a population of T cells under Treg expansion conditions and selecting for CD9+ Tregs. Also provided herein are methods of treating immune disorders with the regulatory B cells and/or regulatory T cells.

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