Substituted β-phenyl-α-hydroxypropionic acid, its synthesis and use

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专利权人:

西北大学

发明人:

ヂョン シャオホイ,ヂャン チュンヂョン,ワン シーシャン,ヂャオ シンフォン

申请号：

JP2009510260

公开号：

JP5094845B2

申请日:

2007.05.14

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention relates to a compound of the formula (I), wherein R 1 , R 2 and R 3 are each independently selected from H, OH, F, Cl, Br, methoxy and ethoxy； or alternatively, R 1 and R 2 together form -OCH 2 O-, R 3 is selected from H, OH, methoxy, ethoxy and halogens； R 4 is OH or acyloxy； R 5 is cycloalkoxyl, amino and substituted amino, and when R 5 is selected from amino, at least one of R 1 , R 2 and R 3 is not H. The present invention further relates to a process for synthesizing a compound of the formula (I), and use of the compound of the formula (I) in the manufacture of a medicament for the prevention or treatment of cardiovascular or cerebrovascular diseases.

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