Minoxidil is to avoid aqueous molecule, insoluble what water but solvable what alcohol and the molten Elixirs of propylene glycol Deng You Machine. During this Hair of are bright, solubility of the minoxidil in water phase is promoted using Two molecules, with The skin Xi Shou Apparatus, (Franz cell) Bi More water solubility minoxidil Pei Fang With fall strong raw Hair water (Regaine) and absorb the good transdermal efficiency of , Knot Guo Hair Now soluble formulation Ju You More in the The skins of big white mouse Pi Skin again.Minoxidil是忌水性分子,不溶於水但可溶於酒精及丙二醇等有機溶劑。在本發明中,利用兩性分子提升minoxidil在水相中的溶解度,再以經皮吸收儀(Franz cell)比較水溶性minoxidil配方與落健生髮水(Regaine)在大白鼠皮膚的經皮吸收,結果發現水溶性配方具有較佳之透皮效率。