PROCÉDÉS D'INHIBITION DE BNIP3 ET MÉTHODES DE PRÉVENTION ET DE TRAITEMENT D'UNE LÉSION D'ISCHÉMIE REPERFUSION PAR L'ACIDE TÉTRA-O-MÉTHYL NORDIHYDROGUAIARÉTIQUE

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专利权人:

THE JOHNS HOPKINS UNIVERSITY

发明人:

HUANG, RU CHIH,KIMURA, KOTOHIKO

申请号：

EP13820143

公开号：

EP2874986A4

申请日:

2013.07.18

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Provided herein are methods for prevention and treatment of ischemia-reperfusion (IR) injury in the cardiac myocytes of a subject, by administration to the subject, a compound of formula I, or a salt, solvate, or stereoisomer thereof, in a sufficient amount either prior to, or during and/or after an ischemic event to mitigate or prevent IR injury to the cardiac tissue. Pharmaceutical compositions including the compound of formula I, or a salt, solvate, or stereoisomer thereof, and/or at least one additional therapeutic agent, are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/