This invention relates to a multifunctional natural wound-healing matrix. The matrix of present invention comprises a wound bed made up of a hydrophilic cotton fabric coated with zwitterionic low molecular weight chitosan on one side and embedded with biosynthesized silver nano-particles on the top of that. There are curcumin particles and tulsi extracts used to enhance its properties with herbal medicinal values further and to provide synergistic effect with all the ingredients working together to provide healthier healing results.