The 4-urea-phenyl substituted 6-morpholin-4-yl-pyrazolo[3,4-d]pyrimidine derivatives are potent and selective inhibitors of mTOR kinase and are useful in treating disorders related to abnormal mTOR activities such as cancer, immune disorders, cardiovascular disease, ocular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders.４－尿素－フェニル置換６－モルホリン－４－イル－ピラゾロ［３，４－ｄ］ピリミジン誘導体は、強力かつ選択的なｍＴＯＲキナーゼ阻害剤であり、異常なｍＴＯＲ活性に関連した障害（癌、免疫不全、心血管病、眼疾患、ウイルス感染、炎症、代謝／内分泌障害および神経障害など）を治療するのに役立つ。
