quinazoline derivatives as nk3 receptor antagonists

• 收藏
• 分享

专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

ANJA LIMBERG,CLAUS RIEMER,HASANE RATNI,HENNER KNUST,MATTHIAS NETTKOVEN,WALTER VIFIAN

申请号：

BRPI0922010

公开号：

BRPI0922010A2

申请日:

2009.11.04

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention relates to a compounds of formula I wherein R1, R2, R3, R4, R5, and n are as defined herein and to a pharmaceutically active salt, a racemic mixture, an enantiomer, an optical isomer or a tautomeric form thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/