LIU XINJUN,KIM PHILLIP,KIRKLAND RICHARD,LEE TANI,YBARRONDO BELEN,SINGH SHARAT
申请号：
NZ60134811
公开号：
NZ601348A
申请日:
2011.01.12
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a method of predicting the response of a triple-negative breast tumor to therapy with an anticancer drug, the method comprising: (a) lysing a tumor cell obtained from the triple-negative breast tumor to produce a cellular extract (b) determining the expression level of VEGFR2 in the cellular extract and (c) comparing the expression level of VEGFR2 in the cellular extract determined in step (b) to a reference expression level of VEGFR2, wherein the presence of a low level of VEGFR2 expression compared to the reference is predictive of response to therapy with the anticancer drug, wherein the anticancer drug is a combination of bevacizumab, carboplatin, and paclitaxel.
