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抗人類Gas6單株抗體
专利权人:
KYOWA HAKKO KIRIN CO.; LTD.
发明人:
UBE, YUKO,宇部优子,宇部優子,YAMADA, TSUYOSHI,山田刚士,山田剛士,YAMAZAKI, YUJI,山崎雄司,KANAME, KIMURA,木村要,HARIGUCHI, AKIKO,播口暁子,OGAWA, SHINYA,小川进也,小川進也
申请号:
TW104134584
公开号:
TW201625682A
申请日:
2015.10.21
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
The present invention pertains to a monoclonal antibody, or an antibody fragment thereof, that binds specifically to human growth arrest-specific 6 (hGas6) and binds to at least one amino acid residue among the 314th, 315th, and 316th amino acid residues of human Gas6. The present invention also pertains to: a nucleic acid containing a base sequence that codes for the antibody or the antibody fragment; a transformed cell containing a vector that contains the nucleic acid; a method for producing the antibody or the antibody fragment; reagents for detecting or measuring Gas6 that contain the antibody or the antibody fragment; therapeutic or diagnostic agents for Gas6-related diseases that contain the antibody or the antibody fragment as an active ingredient; and a use of the antibody or the antibody fragment for producing the therapeutic or diagnostic agents for Gas6-related diseases.本發明係關於一種單株抗體或該抗體片段,該單株抗體係與人類生長抑制特異性蛋白6(hGas6,Human Growth Arrest Specific 6)特異性地結合之抗體,並且與人類Gas6之第314號、第315號及第316號胺基酸殘基中之至少一個胺基酸殘基結合;包含編碼上述抗體或抗體片段之鹼基序列之核酸;包含含有上述核酸之載體之轉形細胞;上述抗體或抗體片段之製造方法;包含上述抗體或抗體片段之Gas6之檢測或測定用試劑;包含上述抗體或抗體片段作為有效成分之Gas6相關疾病之治療藥或診斷藥;或用以製造Gas6相關疾病之治療藥或診斷藥之上述抗體或抗體片段之用途。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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