A novel soybean variety, designated XR39E14 is provided. Also provided are the seeds of soybean variety XR39E14, cells from soybean variety XR39E14, plants of soybean XR39E14, and plant parts of soybean variety XR39E14. Methods provided include producing a soybean plant by crossing soybean variety XR39E14 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XR39E14, methods for producing other soybean varieties or plant parts derived from soybean variety XR39E14, and methods of characterizing soybean variety XR39E14. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XR39E14 are further provided.
