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LIMITING RELATIONS
专利权人:
Cancer Research Technology Limited
发明人:
HOELDER, Swen,BLAGG, Julian,SOLANKI, Savade,WOODWARD, Hannah,BAVETSIAS, Vassilios,SHELDRAKE, Peter,INNOCENTI, Paolo,ATRASH, Butrus,CHEUNG, Kwai-Ming J.,NAUD, Sebastien
申请号:
DK13760106
公开号:
DK2892889T3
申请日:
2013.09.09
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention relates to compounds of formula I wherein R 1 , R 4 , Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1 - also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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