Maribel Guerra Vallespi,Isis del Carmen Torréns Madrazo,Osvaldo Reyes Acosta,Hilda Elisa Garay Pérez,Gerardo Enrique Guillén Nieto,Boris Ernesto Acevedo Castro,Raimundo Ubieta Gómez
申请号:
US12278990
公开号:
US08283324B2
申请日:
2007.02.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is related to the development of peptides derived from the sequence HYRIKPTFRRLKWKYKGKFW (SEQ ID NO.: 13), showing amino acid substitutions, these peptides unable to bind to the lipopolysaccharides and bearing anti-tumoral and immunomodulatory capacities. These peptides alone or in combination are useful to treat cancer, and also in synergy with conventional therapies.