INHIBITION OF TRNA SYNTHETASES AND THERAPEUTIC APPLICATIONS THEREOF

• 收藏
• 分享

专利权人:

Tracy Keller;Malcolm Whitman

发明人:

Malcolm Whitman,Tracy Keller

申请号：

US13201933

公开号：

US20120058133A1

申请日:

2010.02.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides novel methods for modulating Th 17-mediated immune responses using aminoacyl tRNA synthetase inhibitors. Inhibition of aminoacyl tRNA synthetase inhibitors activates an amino acid starvation response (AAR) and can produce beneficial therapeutic effects. In some embodiments, aminoacyl tRNA synthetase inhibitors are used to treat disorders such as autoimmune diseases, graft rejection, infections, fibrosis, and inflammatory diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/