TAN PHILIP H,SIMON SANDY ALEXANDER,CERVENY CHARLES G,NILSSON CHRISTY ANNE,BRADY WILLIAM,LEDBETTER JEFFREY A,HAYDEN-LEDBETTER MARTHA SUSAN,THOMPSON PETER ARMSTRONG,MORALES CECILE
申请号:
ZA201007570
公开号:
ZA201007570B
申请日:
2010.10.22
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B-cell related autoimmune, inflammatory, or hyperproliferative diseases.