Battelle Memorial Institute;Jessica Catherine Bright
发明人:
Brian L. Burback,Jessica Catherine Bright,Jerry D. Johnson
申请号:
US16695306
公开号:
US20200171010A1
申请日:
2019.11.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are methods of reducing muscle contraction in a diaphragm or peripheral muscle(s) of a patient sufficient to permit a surgical procedure. The methods may comprise the step of administering an oxime or pharmaceutically acceptable salt thereof to a subject in need thereof in an amount sufficient to achieve said reduced muscle contraction/neuromuscular blockade. Kits and articles of manufacture comprising a container having a label and a composition are also disclosed.