A method of configuring a prosthesis having two or more electrode contacts, including configuring the prosthesis to provide stimulation to a first tissue site from a subset of electrode contacts based on data based on a comparison of first data to second data, wherein the first data is based on respective estimated voltages for the first site and one or more of additional respective sites to be applied by the subset of electrode contacts, the respective estimated voltages being based on empirical stimulation data for the first and additional sites, and the second data is based on respective target voltages for the first and additional sites, respectively.
