FRED HUTCHINSON CANCER RESEARCH CENTER;ORICULA THERAPEUTICS LLC;UNIVERSITY OF WASHINGTON
发明人:
Julian Simon,Graham Johnson,Edwin W. Rubel,David W. Raible,Mario D. Gonzalez,Peter C. Meltzer,Weishi Miao
申请号：
US15547438
公开号：
US20180022756A1
申请日:
2016.02.05
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing or treating hearing loss. The compounds and pharmaceutical compositions described herein prevent or treat hair cell death. In addition, the compounds and pharmaceutical compositions described herein protect against kidney damage in an individual receiving an aminoglycoside antibiotic. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.
