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Synthesis, Preparation and Use of Dibenzodiazepines
专利权人:
INC.;AUSPEX PHARMACEUTICALS
发明人:
ZHANG, CHENGZHI,KERR, JAMES
申请号:
ARP180100611
公开号:
AR111182A1
申请日:
2018.03.15
申请国别(地区):
AR
年份:
2019
代理人:
摘要:
Dibenzodiazepine analoguesIncluding the same composition and the method for detecting the composition including Dutetrabenzodiazepines. There is also a batch of drug identification process. 1. Characteristic 1: Pharmaceutical ingredients.Characterized by a mixture of a drug, dibenzodiazepines, and an acceptable vehicle on a drug.1. Dibenzodiazepines (1);0.5% area or less than formula compound (2),Concerning the concentration of dibenzodiazepines,According to the calculation results of HPLC and 0.15% area or less than compound formula (3),Concerning the concentration of dibenzodiazepines,According to the determination made by the method of HPLC,There, the drug composition is stable when it is stored at ambient temperatures of 1 to 24 months. 8. Claim 8: The pharmaceutical ingredients of any of the above claims.It's shaped like a capsule.A tabletOr liquid suspended matter 11. Claim 10: The pharmaceutical ingredients of any of the above claims.It is characterized by the presence of 5 to 30 mg of dibenzodiazepines.6 to 24 mg of dibenzodiazepines6 mg dibenzodiazepines9 mg Dibenzodiazepines12 mg dibenzodiazepines15 mg dibenzodiazepines18 mg dibenzodiazepines21 mg dibenzodiazepinesOr 24 mg dibenzodiazepines Requirement 13: Treatment of patients with hyperkinetic dyskinesiaIts characteristics are that it includes the management of the main drug ingredients to meet any of the above requirements. Proposition 17: Approach 13It is characterized by hyperkinetic dyskinesia as an ICT related to Tourette syndrome. Requirement 18: The process of cultivating pharmaceutical ingredients.1. It has mixed drug properties, including dibenzodiazepines (1);0.5% area or less than formula compound (2),Concerning the concentration of dibenzodiazepines,According to the calculation results of HPLC and 0.15% area or less than compound formula (3),Concerning the concentration of dibenzodiazepines,Based on the decision to use a pharmaceutically acceptable vehicle in accordance with the HPLC method.
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