GARIGAPATI, VENKATA R.,盖利格,蓋利格,SU, DONGLING,苏东凌,蘇東凌,SAWAMURA, STEVEN J.,泽村史帝文,澤村史帝文,KHANZADA, REHAN,康雷恩
申请号：
TW096147554
公开号：
TWI419715B
申请日:
2007.12.13
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.本發明係關於各種冷凍乾燥配製物和組成物內之骨成形蛋白的穩定化。本發明的配製物主要包括用於冷凍乾燥組成物及其後儲藏及重構之作為賦形劑的海藻糖以及亦可選擇性地包括其他的賦形劑如緩衝劑和表面活性劑。
