A method and related apparatus are provided for making an ultrasonic irradiation plan include generating a 3D organ model from an input image, generating irradiation information about a unit treatment volume based on at least one of a movement and a deformation of an organ in the 3D organ model, simulating irradiation of ultrasound for virtual treatment by using the generated irradiation information, and making an ultrasonic irradiation plan based on the simulation. Additionally, a method is provided for determining if such an ultrasonic irradiation plan is applicable, and if so carrying it out by emitting appropriate ultrasonic radiation.