Peter Andreas Nicolai Reumert Wagtmann,Francois Romagne,Joakim Glamann
申请号：
US11813399
公开号：
US08551483B2
申请日:
2006.01.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Described are methods of treating viral disease using compounds that block inhibitory NK cell receptors, thereby reducing their inhibition of NK cell cytotoxicity in killing infected target cells. In one embodiment, the compound is an antibody binding, for example, one or more of the human KIR2DL1, KIR2DL2, and KIR2DL3 receptors. In another embodiment, the method further comprises administering a therapeutic antibody or fusion protein which binds an antigen expressed on cells infected with the virus.
